The Armenian National Committee of America (ANCA) is the largest and most influential Armenian American grassroots political organization. They aim to educate, motivate, and activate individuals to take action on various issues, including prioritizing the recognition of the Armenian Genocide, advocating for reparations, supporting Artsakh (Nagorno Karabakh), and fostering strong US-Armenia ties. ANCA offers ways for people to get involved such as donating, joining the ANCA E-List, registering to vote, attending events, and volunteering. The organization also provides resources like news updates, photos, videos, and information on legislative initiatives.

ANCA has been actively involved in advocating for justice for Artsakh and the Armenian Genocide. With a bipartisan coalition of US legislators joining forces to address these issues, ANCA aims to secure support for Armenians affected by these historical events. The organization's work includes urging Congressional leaders to hold Azerbaijan accountable for its actions against Artsakh and calling for measures like suspending military assistance to Azerbaijan. Additionally, ANCA has been engaging in grassroots efforts across different states in the US to rally support for Armenia's security and Artsakh's rights.